Lysine post-translational modifications of collagen

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Lysine post-translational modifications of collagen.

Type I collagen is the most abundant structural protein in vertebrates. It is a heterotrimeric molecule composed of two α1 chains and one α2 chain, forming a long uninterrupted triple helical structure with short non-triple helical telopeptides at both the N- and C-termini. During biosynthesis, collagen acquires a number of post-translational modifications, including lysine modifications, that ...

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ژورنال

عنوان ژورنال: Essays in Biochemistry

سال: 2012

ISSN: 0071-1365,1744-1358

DOI: 10.1042/bse0520113